Author

Karin J. Koymans

University of AmsterdamORCID 0000-0001-6519-7658Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

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August Benjamin SmitiD· 1 shared Helmut W. H. G. KesselsiD· 1 shared Ka Wan LiiD· 1 shared Niels R. Reinders· 1 shared Remco V. KlaasseniD· 1 shared Sophie J. F. van der SpekiD· 1 shared

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1 shared paperNeuroscience

August Benjamin SmitORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintOct 3, 2021

β-amyloid-driven synaptic depression requires PDZ protein interaction at AMPA-receptor subunit GluA3

Niels R. Reinders, Sophie J. F. van der Spek, Remco V. Klaassen…·Helmut W. H. G. Kessels

This study shows that β-amyloid oligomers cause synaptic depression by removing GluA3-containing AMPARs from synapses, requiring PDZ protein interaction.

DOI 10.1101/2021.10.03.462970

experimental assay

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