Author

zhenfei li

Chinese Academy of SciencesORCID 0000-0001-6520-431XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1

Frequent Co-Authors

Denglong WuiD· 2 shared Hanchu YeiD· 2 shared Xinan WangiD· 2 shared Ziqun Liu· 2 shared Chen Wang· 1 shared Chengchao Ruan· 1 shared Chunqiao SuniD· 1 shared Feifei LiniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Denglong WuORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 9, 2026

scPRIME-seq uncovers synchronized multimodal molecular collapse facilitated by pre-neoplastic epigenetic burden in prostate cancer

Shengdi Li, Ziqun Liu, Yingying Xie…·zhenfei li

The paper introduces scPRIME-seq, a multimodal single-cell platform, and finds pre-neoplastic epigenetic changes drive tumor progression in prostate cancer.

DOI 10.64898/2026.10.07.757464

humanscRNA-seq

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Cancer BiologybioRxivPreprintSep 2, 2026

A patient-centric therapeutic paradigm uncouples prostate cancer suppression from systemic metabolic collapse

Ziqun Liu, Hanchu Ye, Haoran Hu…·Zhenfei Li

This paper identifies metabolic dysregulation caused by abiraterone in prostate cancer patients and develops Lifehug-9892 to suppress tumors while preserving systemic metabolic health.

DOI 10.64898/2026.08.30.748180

humanmetabolomics

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