Author

Denglong Wu

Tongji UniversityORCID 0009-0008-0398-7337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Hanchu YeiD· 2 shared Xinan WangiD· 2 shared zhenfei liiD· 2 shared Ziqun Liu· 2 shared Chen Wang· 1 shared Chengchao Ruan· 1 shared Chunqiao SuniD· 1 shared De ChangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Hanchu YeORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 9, 2026

scPRIME-seq uncovers synchronized multimodal molecular collapse facilitated by pre-neoplastic epigenetic burden in prostate cancer

Shengdi Li, Ziqun Liu, Yingying Xie…·zhenfei li

The paper introduces scPRIME-seq, a multimodal single-cell platform, and finds pre-neoplastic epigenetic changes drive tumor progression in prostate cancer.

DOI 10.64898/2026.10.07.757464

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 2, 2026

A patient-centric therapeutic paradigm uncouples prostate cancer suppression from systemic metabolic collapse

Ziqun Liu, Hanchu Ye, Haoran Hu…·Zhenfei Li

This paper identifies metabolic dysregulation caused by abiraterone in prostate cancer patients and develops Lifehug-9892 to suppress tumors while preserving systemic metabolic health.

DOI 10.64898/2026.08.30.748180

humanmetabolomics

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Cancer BiologybioRxivPreprintJul 9, 2025

Granulin+ macrophages promote lineage plasticity in prostate cancer through paracrine signaling loops

Zhipeng Zhu, Mi Zhang, Ying Song…·Fengbiao Mao

This study identifies granulin+ macrophages as drivers of lineage plasticity in prostate cancer through paracrine signaling loops, promoting drug resistance.

DOI 10.1101/2025.07.09.663835

mousescRNA-seq

𝕏 PostBluesky