Ex vivo SIM-AFM measurements reveal the spatial correlation of stiffness and molecular distributions in 3D living tissue
Itsuki Shioka, Ritsuko Morita, Rei Yagasaki…·Satoru Okuda
The paper introduces a new method combining USIM and AFM to measure stiffness and biomolecular distributions in 3D living tissue, revealing mechanical heterogeneity and the role of collagens.