Author

Norman Michael Drzeniek

Berlin-Brandenburger Centrum für Regenerative TherapienORCID 0000-0001-6562-2351Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Dimitrios L. WagneriD· 2 shared Jonas KathiD· 2 shared Michael LaunspachiD· 2 shared Ana-Maria NitulescuiD· 1 shared Andriko PalmowskiiD· 1 shared Anna Luisa HilleriD· 1 shared Annette Kuenkele· 1 shared Antonia M Klaas· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

Dimitrios L. WagnerORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJun 4, 2026

A Non-Viral CRISPR/Cas9 HDR Platform for Stable Engineering of Solid Tumor Models.

Shoaib Afzal, Maximilian Pilgram, Julia Macos…·Michael Launspach

This paper develops a non-viral CRISPR/Cas9 HDR platform for stable transgene knock-in in solid tumor models, achieving up to 60% efficiency in neuroblastoma cells.

DOI 10.64898/2026.06.01.729035

humanCRISPR screen

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BioengineeringMolecular Therapy — Nucleic AcidsPeer-reviewedJan 5, 2026

Revisiting the need for mRNA nucleoside modification in CAR T cell engineering

Nourhan Kahwaji, Niklas Kotzian, Jasmin Melissa Prinz…·Norman Michael Drzeniek

This study shows that unmodified mRNA can be used for CAR-T cell engineering without compromising function, eliminating the need for costly nucleoside modifications.

7 citationstop 1%

humanbulk RNA-seq

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