Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer
Susmita Ghosh, Fan Fan, Reid Trenton Powell, Yong Sung Park, CLIFFORD C. STEPHAN, Scott Kopetz, Lee M. Ellis, Rajat Bhattacharya
This study identifies paclitaxel as a synergistic partner for trametinib in KRAS-mutated colorectal cancer, showing enhanced anti-tumor effects in vitro and in vivo.
Therapeutic Advances in Medical Oncology · Jan 1, 2024Peer-reviewedCancer Biology