Reid Trenton Powell

The paper identifies collateral sensitivity to MEK inhibition in MTAP-null NSCLC cells that develop resistance to PRMT5 inhibitors.

The paper examines the Golgi structure in airway secretory cells, finding a unique combination of a perinuclear Golgi ribbon and dispersed Golgi satellites, independent of mucin production levels.

The paper identifies a druggable groove on DeltaFOSB that allows small molecules to modulate its DNA binding and release, with one compound reducing genomic occupancy by 60% in vivo.

This study identifies a link between the ETV5/p38 signaling axis and aggressive thyroid cancers, showing that combining p38 inhibitors with BRAF inhibitors improves treatment outcomes.

This study identifies a conserved Hippo signaling pathway in C. elegans, showing canonical activity in epithelium and non-canonical regulation in intestine.

This study identifies paclitaxel as a synergistic partner for trametinib in KRAS-mutated colorectal cancer, showing enhanced anti-tumor effects in vitro and in vivo.