Author

Dangliang Liu

Peking UniversityORCID 0000-0001-6598-8871Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Aoxuan Zhang· 1 shared Arieh WarsheliD· 1 shared Ashim NandiiD· 1 shared Qijia WeiiD· 1 shared Suwei DongiD· 1 shared Wen Jun XieiD· 1 shared Xiaoya WangiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Aoxuan Zhang

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1 paper

Recent·Most cited

BioinformaticsProceedings of the National Academy of SciencesPeer-reviewedNov 20, 2023

Enhancing Luciferase Activity and Stability through Generative Modeling of Natural Enzyme Sequences

Wen Jun Xie, Dangliang Liu, Xiaoya Wang…·Arieh Warshel

This study uses generative modeling and biochemistry to improve luciferase activity and stability by engineering its active center and scaffold, achieving a 50% success rate for single mutants.

27 citations

protein sequencestatistical model

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