Natalia Lopez‐Barbosa

This study presents the first cryo-EM structures of Asgard chromatin assemblies, revealing closed and open hypernucleosome conformations and their evolutionary implications.

This study enhances the affinity and cytotoxicity of an anti-polysialic acid antibody through rational design and directed evolution, resulting in more potent variants.

The paper describes a method to isolate full-length IgG antibodies from combinatorial libraries in E. coli using a bifunctional antigen substrate for selection.