Author

Tobias Reiff

Heinrich Heine University DüsseldorfORCID 0000-0001-6610-6148Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Barak RotblatiD· 2 shared Daniel J. PicardiD· 2 shared Gabriel LeprivieriD· 2 shared Guido ReifenbergeriD· 2 shared Marc RemkeiD· 2 shared Oksana Lewandowska· 2 shared Alberto DelaidelliiD· 1 shared Bastian Görlich· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersCancer Biology

Barak RotblatORCID

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3 papers

Recent·Most cited

Cancer BiologyCell Death DiscoveryPeer-reviewedJul 16, 2025

The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma

Laura Hruby, Katerina Schaal, Alberto Delaidelli…·Gabriel Leprivier

This study shows that EIF4EBP1 is upregulated by MYC in medulloblastoma and linked to poorer patient survival.

3 citations

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJan 27, 2024

Oncogenic RAS signaling is a tumor cell-intrinsic determinant of ferroptosis suppression via induction of the GCH1/BH4 axis

Jonathan K. M. Lim, Frauke Stölting, Dennis Roth…·Gabriel Leprivier

This study shows oncogenic RAS signaling suppresses ferroptosis by upregulating GCH1 and BH4, making RAS-driven cancers resistant to ferroptosis-inducing agents.

1 citation

humanbulk RNA-seq

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Developmental BiologyeLifePeer-reviewedAug 10, 2020

Ecdysone steroid hormone remote controls intestinal stem cell fate decisions via the PPARγ-homolog Eip75B in Drosophila

Lisa Zipper, Denise Jassmann, Sofie Burgmer…·Tobias Reiff

This study shows 20HE signaling via Eip75B directs ISC fate to absorptive enterocytes in Drosophila, linking systemic hormones to local stem cell decisions.

98 citationstop 4%

Drosophilaexperimental assay

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