Author

Jesse D. Rogers

Clemson UniversityORCID 0000-0001-6667-2342Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

William J. RichardsoniD· 2 shared Brian A. AguadoiD· 1 shared Kelsey M. WattsiD· 1 shared Kristi S. AnsethiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersSystems Biology

William J. RichardsonORCID

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2 papers

Recent·Most cited

Systems BiologyProceedings of the National Academy of SciencesPeer-reviewedFeb 18, 2022

Network Modeling Predicts Personalized Gene Expression and Drug Responses in Valve Myofibroblasts Cultured with Patient Sera

Jesse D. Rogers, Brian A. Aguado, Kelsey M. Watts…·William J. Richardson

The paper uses network modeling to predict gene expression and drug responses in valve myofibroblasts exposed to patient sera, linking fibrosis-related signaling to AVS severity and identifying potential therapeutic targets.

26 citationstop 5%

humanbulk RNA-seq

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Systems BiologyeLifePeer-reviewedFeb 9, 2022

Fibroblast Mechanotransduction Network Predicts Targets for Mechano-Adaptive Infarct Therapies

Jesse D. Rogers, William J. Richardson

The paper predicts mechano-adaptive therapies for myocardial infarction by modeling fibroblast mechanotransduction and identifying 13 drug targets that modulate matrix accumulation in specific regions.

20 citations

humanstatistical model

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