Kelsey M. Watts

The paper examines sex-specific regulation of EndMT in atherosclerosis using bulk RNA-seq and single-cell transcriptomics, identifying key regulators and stage-dependent differences.

The paper develops sex-specific computational models of cardiac fibroblast networks to identify drug targets for fibrosis, finding potential pathways and explaining sex differences in fibrosis development.

The paper uses network modeling to predict gene expression and drug responses in valve myofibroblasts exposed to patient sera, linking fibrosis-related signaling to AVS severity and identifying potential therapeutic targets.