BiochemistrybioRxivPreprint
Cryo-EM structures of apo human Factor XIa reveal catalytic-domain flexibility and exposure of the Factor IX-binding site
Alena I. Siutkina, Alexander Neuhaus, Marvin Taterra…·Dmitrii V. Kalinin
This study uses cryo-EM to show that Factor XIa exists as a dynamic ensemble with flexible catalytic domains that expose the Factor IX-binding site.