Alexander Neuhaus

This study uses cryo-EM to show that Factor XIa exists as a dynamic ensemble with flexible catalytic domains that expose the Factor IX-binding site.

This paper proposes a multi-scale model of the pyruvate dehydrogenase complex (PDHc) revealing a nested shell structure that coordinates enzyme communication during pyruvate oxidation.

The paper reports cryo-EM structures of UapA, revealing the role of water, lipids, and the N-tail in its transport mechanism and subcellular trafficking.