Author

Shuling Guo

Ionis Pharmaceuticals (United States)ORCID 0000-0001-6703-9303Unclaimed ORCID profile · follow to get notified of new preprints

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Shuling Guo2 papers · Wuhan University

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Courtney J. MercadanteiD· 2 shared Heather L. Kowalski· 2 shared Jared Z. Zhang· 2 shared Mariam Aghajan· 2 shared Milankumar PrajapatiiD· 2 shared Thomas Benedict BartnikasiD· 2 shared Barry Chi Hong LaiiD· 1 shared Bradley Delaney· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersGenetics

Courtney J. MercadanteORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintJul 17, 2024

Manganese transporter SLC30A10 and iron transporters SLC40A1 and SLC11A2 impact dietary manganese absorption

Milankumar Prajapati, Jared Z. Zhang, Grace S Chong…·Thomas Benedict Bartnikas

The paper shows that SLC30A10 deficiency leads to increased manganese absorption via iron transporters SLC11A2 and SLC40A1, contributing to manganese excess and disease.

1 citation

mouseexperimental assay

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GeneticsbioRxivPreprintFeb 20, 2023

Hypoxia-inducible factor 2 is a key determinant of manganese excess and polycythemia in SLC30A10 deficiency

Milankumar Prajapati, Jared Z. Zhang, Courtney J. Mercadante…·Thomas Benedict Bartnikas

This study identifies HIF2 as a key driver of erythropoietin excess and polycythemia in SLC30A10 deficiency by linking manganese toxicity to altered hepatic gene expression and hepcidin regulation.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky