NeurosciencebioRxivPreprint
Activity of prefrontal cortex serotonin 2A receptor expressing neurons is necessary for the head-twitch response of mice to psychedelic drug DOI in a sex-dependent manner
Annika B. Ozols, Jing Wei, Janet M. Campbell…·Amelia L. Gallitano
This study shows that activating prefrontal cortex 5-HT2AR neurons alone does not induce head-twitch responses in mice, but their inhibition prevents DOI-induced responses, with sex-dependent effects.
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