Amelia L. Gallitano

This study shows that deleting EGR3 in Kcna1-null mice rescues seizures, behavior, and brain pathology, linking early seizures to long-term transcriptional changes.

This study shows that activating prefrontal cortex 5-HT2AR neurons alone does not induce head-twitch responses in mice, but their inhibition prevents DOI-induced responses, with sex-dependent effects.

The paper identifies Egr3-dependent genes in mice hippocampi after ECS, finding genes related to DNA damage response and schizophrenia.

Sleep deprivation rapidly increases serotonin 2A receptor expression in the mouse frontal cortex through the immediate early gene Egr3.