Author

Emily Roberts

University of Kansas Medical CenterORCID 0000-0001-6710-0530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Sornakala GaneshkumariD· 2 shared Sumedha GunewardenaiD· 2 shared Vargheese M. ChennathukuzhiiD· 2 shared Aishwarya V. BhurkeiD· 1 shared Ripla AroraiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersPhysiology

Sornakala GaneshkumarORCID

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2 papers

Recent·Most cited

PhysiologyPNAS NexusPeer-reviewedJan 24, 2025

Loss of PRICKLE1 leads to abnormal endometrial epithelial architecture, decreased embryo implantation, and reduced fertility in mice.

Emily Roberts, Aishwarya V. Bhurke, Sornakala Ganeshkumar…·Vargheese M. Chennathukuzhi

This study shows that loss of PRICKLE1 in mouse endometrial epithelium causes abnormal architecture, reduced implantation, and infertility by disrupting cell polarity, cytokinesis, and epithelial-mesenchymal transition.

3 citations

mouseimaging

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PhysiologyReproductionPeer-reviewedDec 16, 2024

Loss of PRICKLE1 in the myometrium leads to reduced fertility, abnormal myometrial architecture, and aberrant extracellular matrix deposition in mice.

Emily Roberts, Sornakala Ganeshkumar, Sumedha Gunewardena, Vargheese M. Chennathukuzhi

This study shows that loss of Prickle1 in mouse myometrium causes uterine leiomyoma-like features, including altered collagen, ECM deposition, and Wnt/PCP signaling disruption.

1 citation

mouseexperimental assay

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