Philip C. Smith

This study shows that astrocyte-specific deletion of Bmal1 disrupts circadian rhythms in perineuronal nets, synaptic plasticity, and learning behavior.

This study identifies the median preoptic nucleus as a key site where estradiol regulates sleep-wake behavior in female rats, showing sex-specific effects and receptor-dependent mechanisms.

This study investigates how estradiol affects adenosinergic signaling and NREM sleep need in adult female rats, finding that estradiol increases extracellular adenosine and blocks A2A receptor effects in the MnPO.