Emmanuel Marquez Legorreta

NucLogic provides a fast and robust 3D nuclear segmentation method that outperforms existing tools at low SNR and enables quantitative analysis of challenging biological imaging data.

The paper develops WARP, a platform integrating neuronal activity and gene expression data in zebrafish brains, revealing functional roles of molecularly defined cell populations and their activity correlations.

SpotDMix improves mRNA spot assignment to cells in spatial transcriptomics by using a mixture model and EM algorithm, outperforming simple methods in accuracy and exclusivity.

The paper uses calcium imaging to study brain-wide visual habituation networks in zebrafish, finding altered network dynamics in fmr1 mutants linked to slower habituation.