Luuk Willem Hesselink

The paper develops WARP, a platform integrating neuronal activity and gene expression data in zebrafish brains, revealing functional roles of molecularly defined cell populations and their activity correlations.

SpotDMix improves mRNA spot assignment to cells in spatial transcriptomics by using a mixture model and EM algorithm, outperforming simple methods in accuracy and exclusivity.

This paper introduces the Recurrent Temporal RBM (RTRBM) to capture both stochastic and time-predictive neural dynamics in whole-brain activity, showing improved generalization and temporal accuracy over previous methods.