Author

James Frank Cnota

Cincinnati Children's Hospital Medical CenterORCID 0000-0001-6732-8949Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Developmental Biology· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:experimental assay· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Helen N JonesiD· 3 shared Alyssa Tipler· 2 shared Jennifer A. Courtney· 2 shared Brian W. McCrindleiD· 1 shared Chitra RavishankariD· 1 shared Daniel BernsteiniD· 1 shared Edgar Javier HernandeziD· 1 shared Elizabeth GoldmuntziD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Helen N JonesORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 27, 2026

Plasma Extracellular Vesicle and miRNA Profiles in Pregnancies Complicated by Fetal Congenital Heart Defects

Alyssa Tipler, Marcella Rodriquez, Mayu Morita…·Helen N Jones

This study examines extracellular vesicles and miRNA profiles in maternal and umbilical cord plasma from pregnancies with fetal congenital heart defects compared to controls, finding altered EV counts and miRNA levels.

DOI 10.64898/2026.05.23.727381

humanbulk RNA-seq

𝕏 PostBluesky

Genetic & Genomic MedicineCommunications MedicinePeer-reviewedSep 27, 2023

Genetic, demographic and clinical variables act synergistically to impact neurodevelopmental outcomes in children with single ventricle heart disease

Thomas A. Miller, Edgar Javier Hernandez, James William Gaynor…·Martin Tristani‐Firouzi

The paper examines how genetic, demographic, and clinical factors interact to influence neurodevelopmental outcomes in children with single ventricle heart disease.

9 citations

humanBayesian inference

𝕏 PostBluesky

GeneticsScientific ReportsPeer-reviewedJun 24, 2022

Analysis of commonly expressed genes between first trimester fetal heart and placenta cell types in the context of congenital heart disease

Rebecca L. Wilson, Victor Yuan, Jennifer A. Courtney…·Helen N Jones

23 citations

humanscRNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintSep 2, 2020

Impaired labyrinth formation prevents the establishment of the maternal-fetal interface in conditional Hand1-deficient mice

Jennifer A. Courtney, James Frank Cnota, Helen N Jones

This study shows that Hand1 deficiency in mice leads to impaired placental labyrinth formation and vascularization, causing embryonic lethality and linking Hand1 to placental development in CHD.

1 citation

mouseexperimental assay

𝕏 PostBluesky