Victor Yuan

The paper introduces tidyomics, an ecosystem bridging Bioconductor and tidy R to streamline omic analysis using data from the Human Cell Atlas.

eoPred predicts the placental phenotype of early-onset preeclampsia using a 45 CpG DNA methylation signature, showing high performance in cross-validation and validation cohorts.

The paper identifies sex-associated differentially methylated CpGs in term placenta DNA using two cohorts and links them to maternal age and birthweight.

The paper develops PlaNET, a DNA methylation-based ethnicity classifier for placental samples, achieving high accuracy and outperforming existing methods in population stratification correction.

This study shows low oxygen promotes extravillous trophoblast differentiation in a human placental explant model by enhancing EVT lineage commitment and LOX activity.