Author

Maria E. Falzone

Howard Hughes Medical InstituteORCID 0000-0001-6738-7017Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Kristin E. CanoiD· 1 shared Makayla A. Crawford· 1 shared Marie B. BennettiD· 1 shared Priyam BanerjeeiD· 1 shared Rahul MojidraiD· 1 shared Roderick MacKinnoniD· 1 shared Taylor G Gonzalez· 1 shared Yu Qin· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperBiophysics

Kristin E. CanoORCID

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2 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedJul 27, 2026

PLCβs are recruited to the plasma membrane in macrophages by both Gβγ and Gαq

Maria E. Falzone, Priyam Banerjee, Roderick MacKinnon

This study shows that PLCβ3 is recruited to the plasma membrane by both Gβγ and Gq in macrophages, revealing dual mechanisms for G protein-dependent regulation of PLCβ enzymes.

DOI 10.1073/pnas.2603275123

mouseproteomics

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BiophysicsbioRxivPreprintJul 21, 2026

Anionic lipids regulate PLCβ membrane recruitment

Makayla A. Crawford, Marie B. Bennett, Yu Qin…·Maria E. Falzone

This study shows that anionic lipids are essential for PLCβ membrane recruitment and modulate Gβγ-dependent activation, highlighting the role of membrane electrostatics in signal transduction.

DOI 10.64898/2026.07.20.739664

experimental assaycell signaling & trafficking

𝕏 PostBluesky