Priyam Banerjee

The paper uses multi-omics approaches to study post-translational changes in macrophages during activation, identifying endosomal mRNA transport as a target of inflammation.

The paper shows E-cadherin redistribution creates tension heterogeneity, triggering cell competition that eliminates pre-malignant cells, but this system can fail, leading to tumor susceptibility.

This study shows that PLCβ3 is recruited to the plasma membrane by both Gβγ and Gq in macrophages, revealing dual mechanisms for G protein-dependent regulation of PLCβ enzymes.

The paper identifies PLSCR1 as a host factor restricting SARS-CoV-2 entry, which recent variants have evolved to bypass, through a CRISPR screen and integration of genetic studies.