Imtiaz Hossain

This study shows that mutant huntingtin spreads across neuromuscular junctions, causing muscle pathology in human cells and mice, suggesting transmission as a therapeutic target for neurodegenerative diseases.

This paper introduces metadata-guided visual representation learning for clustering biomedical images without image-level annotations, showing it effectively groups images by phenotype.

This paper develops an image-based assay with machine learning to profile beta-lactam antibiotic activity in E. coli by analyzing morphological changes linked to PBP specificity.

This paper develops an unsupervised deep learning method for analyzing cellular images to identify phenotypes and compound effects without segmentation or manual annotations.