Author

Katsuya Ohbuchi

Tsumura (Japan)ORCID 0000-0001-6756-3260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Hiroshi TsugawaiD· 3 shared Mi Hwa Chung· 3 shared Taiki NakayaiD· 3 shared Hina Sakai· 2 shared Hiroyuki YamamotoiD· 2 shared Kazunori SasakiiD· 2 shared Kazuya TsumagariiD· 2 shared Koshi ImamiiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersBiochemistry

Hiroshi TsugawaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 8, 2026

Elucidation of the anti-inflammatory mechanism of isoliquiritigenin from Glycyrrhiza uralensis using activity-based protein profiling

Hina Sakai, Mi Hwa Chung, Taiki Nakaya…·Hiroshi Tsugawa

This study identifies L-PGDS as a covalent target of isoliquiritigenin, revealing its anti-inflammatory mechanism through suppression of PGD2 production.

DOI 10.64898/2026.05.05.722967

proteomicsexperimental assay

𝕏 PostBluesky

Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedDec 13, 2025

Unraveling anti-inflammatory metabolic signatures of Glycyrrhiza uralensis and isoliquiritigenin through multiomics

Saki Kiuchi, Mi Hwa Chung, Hina Sakai…·Hiroshi Tsugawa

This study uses multiomics to analyze the anti-inflammatory effects of Glycyrrhiza uralensis and isoliquiritigenin in macrophages, identifying metabolic and phosphorylation changes associated with inflammation suppression.

3 citations

metabolomicsproteomics

𝕏 PostBluesky

BiochemistryJournal of the American Society for Mass SpectrometryPeer-reviewedAug 13, 2024

Using variable data independent acquisition for capillary electrophoresis-based untargeted metabolomics

Saki Kiuchi, Yasuhiro Otoguro, Tomoaki Nitta…·Hiroshi Tsugawa

This study evaluates DIA techniques for CE-MS/MS metabolomics, showing vDIA with MS-DIAL improves annotation rates and accuracy, and identifies new metabolites in LPS-treated macrophages.

5 citations

metabolomicsdeep learning

𝕏 PostBluesky