Kazuya Tsumagari

This study identifies L-PGDS as a covalent target of isoliquiritigenin, revealing its anti-inflammatory mechanism through suppression of PGD2 production.

This paper introduces Rapid HAMMOC, a phosphoproteomics workflow that improves sensitivity and reduces sample loss, identifying more phosphosites from low-input samples.

This study uses multiomics to analyze the anti-inflammatory effects of Glycyrrhiza uralensis and isoliquiritigenin in macrophages, identifying metabolic and phosphorylation changes associated with inflammation suppression.

This study uses quantitative proteomics to analyze age-related changes in mouse brain tissues, identifying age-associated upregulation of extracellular proteins and downregulation of synaptic proteins.

The paper identifies cleavage sites of ectodomain shedding in 10 human cell lines using mass spectrometry and finds 411 cleavage sites on 132 membrane proteins.

This study identifies RseP as an intramembrane protease that cleaves FecR, a regulator of ferric citrate uptake, revealing a novel role in iron homeostasis in E. coli.