Li‐Shiun Chen

This paper develops a polygenic score for smoking persistence and finds it is associated with earlier or later cessation ages across diverse populations.

The paper develops polygenic risk scores to stratify lung cancer and smoking cessation risk, showing significant odds ratios in diverse populations and planning clinical trials to evaluate interventions.

This study conducts a trans-ancestral GWAS of alcohol dependence, identifying genetic variants and correlations with psychiatric disorders.

The paper investigates the genetic link between schizophrenia and substance use disorder, finding shared polygenic liability across multiple datasets.