Emir Maldosevic

The paper determines the structure of the ribosome stalled by the AMD1 C-tail, revealing how it traps eRF1 and ABCE1 to block translation termination.

This study identifies a molecular switch in NAC that prevents mitochondrial protein mistargeting by SRP, showing that mutations disrupt this mechanism and cause ER stress.

The paper reports the cryo-EM structure of the mammalian SEL1L-HRD1 ERAD core complex, revealing its dimeric organization and how pathogenic mutations disrupt its function and contribute to disease.