Author

Mateusz Szczerba

Harvard UniversityORCID 0000-0001-6820-8076Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

Marcia B. GoldbergiD· 2 shared Akshaya GaneshiD· 1 shared María Luisa Gil-Marqués· 1 shared Volker BrikeniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersImmunology

Marcia B. GoldbergORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 11, 2026

Dual NLRC4 and non-canonical inflammasome signaling drives human GSDMD-mediated killing of Shigella flexneri independently of bacterial cardiolipin.

Mateusz Szczerba, Marcia B. Goldberg

This study shows that human macrophages use both NLRC4 and non-canonical inflammasome pathways to kill Shigella flexneri without causing cell death, independent of bacterial cardiolipin.

DOI 10.64898/2026.01.11.698901

humanproteomics

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ImmunologymBioPeer-reviewedApr 24, 2025

NLRP11 is required for canonical NLRP3 and non-canonical inflammasome activation during human macrophage infection with mycobacteria

Mateusz Szczerba, Akshaya Ganesh, María Luisa Gil-Marqués…·Marcia B. Goldberg

11 citations

humanexperimental assay

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