Clonal Hematopoiesis Accelerates Frailty and Functional Decline
Kun Zhao, Candice Quin, Yash Pershad…·Alexander G. Bick
This study links clonal hematopoiesis to accelerated frailty and functional decline across multiple organ systems in humans.
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McMaster UniversityORCID 0000-0001-6823-2957Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
7 papers
Recent·Most cited
Kun Zhao, Candice Quin, Yash Pershad…·Alexander G. Bick
This study links clonal hematopoiesis to accelerated frailty and functional decline across multiple organ systems in humans.
Christian J. Bellissimo, Tatiane Aparecida Ribeiro, Erica Yeo…·Deborah Magdalena Sloboda
This study shows that maternal high-fat, high-sucrose diet leads to placental hypoxia and immune disruption in late gestation without significant fetal growth issues.
Christian J. Bellissimo, Erica Yeo, Tatiane Aparecida Ribeiro…·Deborah Magdalena Sloboda
Anna Woo Bentz, Monica A. Gutierrez, Dessi Loukov…·Deborah R. Winter
This study identifies distinct TNF-dependent aging signatures in monocyte subpopulations, showing that aging affects their transcriptional regulation differently.
Tatiane Aparecida Ribeiro, Jessica A. Breznik, Katherine M. Kennedy…·Deborah Magdalena Sloboda
This study examines how pregnancy and adiposity affect intestinal structure, permeability, and immune cell composition in mice at mid- and late-gestation.
Jessica A. Breznik, Tatiane Aparecida Ribeiro, Erica Yeo…·Deborah Magdalena Sloboda
This study examines how diet-induced excess adiposity in mice affects maternal physiological adaptations during lactation and postpartum health.
Darren Fernandes, Shoshana Spring, Christina Corre…·Jason P. Lerch
The paper uses MRI and Bayesian hierarchical modeling to show that immune dysfunction in mice affects specific brain regions and correlates with anxiety-like behaviors.