Ziyang Liu

This paper introduces an iterative method to improve nanopore sequencing basecalling accuracy for therapeutic RNA quality control, enabling precise analysis of modified RNAs.

This paper develops a basecalling scheme for short-read nanopore sequencing, showing improved accuracy using bioengineered RNA molecules.

This paper adapts nanopore sequencing basecalling models for modification detection using incremental learning and anomaly detection, achieving single-molecule and single-nucleotide resolution across multiple species and modification types.