Myeloperoxidase (MPO) exacerbates dengue-associated liver injury and contributes to disease pathogenesis in mouse models
Carla Bianca Luena Victorio, Andrew Teo, Shantanu Gupta, Arun Ganasarajah, Joanne Ong, Jasmine SK, Kíssila Rabelo, Luciana Lontro Alves, Carlos Alberto Basílio‐de‐Oliveira, Rodrigo Panno Basílio-de-Oliveira, Po Ying Chia, Heshan Kuruppu, Maneshka Vindesh Karunananda, Damayanthi Idampitiya, Ananda Wijewickrama, , Ann‐Marie Chacko
This study shows that myeloperoxidase worsens liver damage in dengue by causing oxidative stress and inflammation in mouse models.
bioRxiv · Aug 27, 2026 · PreprintPathology