Author

Sharon Nienyun Hsu

University of SheffieldORCID 0000-0003-2356-9155Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Organism:virus· 1

Frequent Co-Authors

Benjamin B. LindseyiD· 2 shared Matthew D. ParkeriD· 2 shared Thushan I. de SilvaiD· 2 shared Alexander James KeeleyiD· 1 shared Alison Cope· 1 shared Amy State· 1 shared Ananda WijewickramaiD· 1 shared Benjamin H. FoulkesiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Benjamin B. LindseyORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Genomic and epidemiological analysis of SARS-CoV-2 viruses in Sri Lanka

Chandima Jeewandara, Deshni Jayathilaka, D.M.S.H.K. Ranasinghe, Sharon Nienyun Hsu, Dinuka Ariyaratne, Tibutius T. P. Jayadas, Deshan Madusanka, Benjamin B. Lindsey, Laksiri Gomes, Matthew D. Parker, Ananda Wijewickrama, Malika Karunaratne, Graham Stuart Ogg, Thushan I. de Silva, Gathsaurie Neelika Malavige

The paper analyzes SARS-CoV-2 genomic sequences from Sri Lanka to track lineage prevalence and transmission patterns, finding B.1.411 was dominant until B.1.1.7 replaced it in late 2020.

Frontiers in Microbiology · Sep 16, 2021Peer-reviewedGenetic & Genomic Medicine

Altered Subgenomic RNA Expression in SARS-CoV-2 B.1.1.7 Infections

Matthew D. Parker, Benjamin B. Lindsey, Dhruv R. Shah, Sharon Nienyun Hsu, Alexander James Keeley, David George Partridge, Shay Leary, Alison Cope, Amy State, Katie Johnson, Nasar Ali, Rasha Raghei, Joe Heffer, Darren Smith, Peijun Zhang, , Thushan I. de Silva

The paper shows that B.1.1.7 SARS-CoV-2 lineage has increased subgenomic RNA expression compared to other lineages, with a noncanonical sgRNA near ORF9b showing a 16-fold increase in median expression.

bioRxiv · Mar 2, 2021 · PreprintGenomics