Human Nucleolar Protein 7 (NOL7) is required for pre-rRNA transcription and pre-18S rRNA processing
Mason A. McCool, Carson J. Bryant, Hannah Huang, Lisa M. Ogawa, Katherine I. Farley‐Barnes, Samuel B. Sondalle, Laura Abriola, Yulia V. Surovtseva, Susan J. Baserga
This study identifies NOL7 as the human ortholog of yeast Bud21, showing its essential role in pre-rRNA transcription and pre-18S rRNA processing, with consequences for protein synthesis and cell cycle progression.
bioRxiv · Nov 8, 2022 · PreprintMolecular Biology