Author

Laura Abriola

Yale UniversityORCID 0000-0002-7304-6531Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Yulia V. SurovtsevaiD· 4 shared Brett D. LindenbachiD· 2 shared Carson J. BryantiD· 2 shared Craig B. WileniD· 2 shared Mason A. McCooliD· 2 shared Mia Madel AlfajaroiD· 2 shared Susan J. BasergaiD· 2 shared Benhur LeeiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersMolecular Biology

Yulia V. SurovtsevaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The cytidine deaminase APOBEC3A is required for large ribosomal subunit biogenesis

Mason A. McCool, Carson J. Bryant, Laura Abriola, Yulia V. Surovtseva, Susan J. Baserga

This study identifies APOBEC3A as a novel factor required for ribosome biogenesis and shows its role in editing pre-rRNA and pre-mRNA.

bioRxiv · Feb 20, 2023 · PreprintMolecular Biology

Human Nucleolar Protein 7 (NOL7) is required for pre-rRNA transcription and pre-18S rRNA processing

Mason A. McCool, Carson J. Bryant, Hannah Huang, Lisa M. Ogawa, Katherine I. Farley‐Barnes, Samuel B. Sondalle, Laura Abriola, Yulia V. Surovtseva, Susan J. Baserga

This study identifies NOL7 as the human ortholog of yeast Bud21, showing its essential role in pre-rRNA transcription and pre-18S rRNA processing, with consequences for protein synthesis and cell cycle progression.

bioRxiv · Nov 8, 2022 · PreprintMolecular Biology

Restriction of SARS-CoV-2 Replication by Targeting Programmed -1 Ribosomal Frameshifting In Vitro

Yu Sun, Laura Abriola, Rachel O. Niederer, Savannah F. Steinhauser, Mia Madel Alfajaro, Valter Silva Monteiro, Craig B. Wilen, Ya‐Chi Ho, Wendy V. Gilbert, Yulia V. Surovtseva, Brett D. Lindenbach, Junjie U. Guo

This study identifies merafloxacin as a -1 PRF inhibitor that impedes SARS-CoV-2 replication in vitro.

Proceedings of the National Academy of Sciences · Jun 14, 2021Peer-reviewedMolecular Biology

Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection

Jin Wei, Mia Madel Alfajaro, Ruth E. Hanna, Peter C. DeWeirdt, Madison S. Strine, William J. Lu-Culligan, Shang‐Min Zhang, Vincent R. Graziano, Cameron O. Schmitz, Jennifer Chen, Madeleine C. Mankowski, Renata B. Filler, Victor Gasque, Fernando de Miguel, Huacui Chen, , Craig B. Wilen

A genome-wide CRISPR screen with SARS-CoV-2 recovers ACE2 and Cathepsin L and nominates SWI/SNF, TGF-beta signalling and HMGB1 as pro-viral; pathway inhibitors blocked virus-induced death.

bioRxiv · Jun 16, 2020 · PreprintGenetics