Author

Carson J. Bryant

Yale UniversityORCID 0000-0002-7475-875XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Susan J. BasergaiD· 3 shared Laura AbriolaiD· 2 shared Mason A. McCooliD· 2 shared Yulia V. SurovtsevaiD· 2 shared Alexandra KhituniD· 1 shared Anil VasudevaniD· 1 shared Cecelia M. HaroldiD· 1 shared Danny IncarnatoiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersMolecular Biology

Susan J. BasergaORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Physicochemical Principles Driving Small Molecule Binding to RNA

Timothy E. H. Allen, James L. McDonagh, Malgorzata Broncel, Carson J. Bryant, Danny Incarnato, Anil Vasudevan, Rabia T. Khan

The paper derives physicochemical rules for small molecule binding to RNA using extensive binding data and applies them to validate known RNA-targeting compounds and drugs.

bioRxiv · Jan 31, 2024 · PreprintBioinformatics

The cytidine deaminase APOBEC3A is required for large ribosomal subunit biogenesis

Mason A. McCool, Carson J. Bryant, Laura Abriola, Yulia V. Surovtseva, Susan J. Baserga

This study identifies APOBEC3A as a novel factor required for ribosome biogenesis and shows its role in editing pre-rRNA and pre-mRNA.

bioRxiv · Feb 20, 2023 · PreprintMolecular Biology

Human Nucleolar Protein 7 (NOL7) is required for pre-rRNA transcription and pre-18S rRNA processing

Mason A. McCool, Carson J. Bryant, Hannah Huang, Lisa M. Ogawa, Katherine I. Farley‐Barnes, Samuel B. Sondalle, Laura Abriola, Yulia V. Surovtseva, Susan J. Baserga

This study identifies NOL7 as the human ortholog of yeast Bud21, showing its essential role in pre-rRNA transcription and pre-18S rRNA processing, with consequences for protein synthesis and cell cycle progression.

bioRxiv · Nov 8, 2022 · PreprintMolecular Biology

Nascent alt-protein chemoproteomics reveals a repressor of ribosome biogenesis

Xiongwen Cao, Alexandra Khitun, Cecelia M. Harold, Carson J. Bryant, Shu-Jian Zheng, Susan J. Baserga, Sarah A. Slavoff

The paper identifies nascent alternative proteins in human cells using chemoproteomics and shows one represses ribosome biogenesis.

bioRxiv · Jun 29, 2021 · PreprintMolecular Biology