Yulia V. Surovtseva

The paper introduces a platform to identify condensate modulators linked to neurological disorders using chemical and genetic screens.

This paper introduces FastBindRank, a distillation-based framework for high-fidelity virtual screening of large chemical libraries, achieving higher hit rates and discovery yields than traditional methods.

This study identifies APOBEC3A as a novel factor required for ribosome biogenesis and shows its role in editing pre-rRNA and pre-mRNA.

This study identifies NOL7 as the human ortholog of yeast Bud21, showing its essential role in pre-rRNA transcription and pre-18S rRNA processing, with consequences for protein synthesis and cell cycle progression.

The paper identifies genes with low mutation frequency but significant functional impact in 17 cancer types using network propagation, finding 8 previously unreported genes.

This study identifies merafloxacin as a -1 PRF inhibitor that impedes SARS-CoV-2 replication in vitro.

A genome-wide CRISPR screen with SARS-CoV-2 recovers ACE2 and Cathepsin L and nominates SWI/SNF, TGF-beta signalling and HMGB1 as pro-viral; pathway inhibitors blocked virus-induced death.