Developmental BiologybioRxivPreprint
Changing the Waddington landscape to control mesendoderm competence
James R. Valcourt, Roya E. Huang, Sharmistha Kundu…·Sharad Ramanathan
This study shows that mesendoderm competence in differentiating human pluripotent stem cells can be modulated by genetic perturbations and tracked using a low-dimensional reaction coordinate.
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