Divya Venkatasubramanian

Leveraging single cell multiomic analyses to identify factors that drive human chondrocyte cell fate

This study uses single-cell multiomic data to identify transcription factors and regulatory networks driving human chondrocyte differentiation and cartilage development.

Lineage-Specific Differences and Regulatory Networks Governing Human Chondrocyte Development

The paper generates human articular and growth plate chondrocytes from stem cells, maps their regulatory networks, and identifies lineage-specific transcription factors.

Changing the Waddington landscape to control mesendoderm competence

This study shows that mesendoderm competence in differentiating human pluripotent stem cells can be modulated by genetic perturbations and tracked using a low-dimensional reaction coordinate.