Author

Sharmistha Kundu

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Robert E. KingstoniD· 3 shared Alexander Morris· 2 shared Anthony Ducasse· 2 shared Ruslan I. SadreyeviD· 2 shared Alicia SolórzanoiD· 1 shared Anthony N. AnselmoiD· 1 shared Ayla ErgüniD· 1 shared Azadeh PaksaiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMolecular Biology

Robert E. KingstonORCID

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4 papers

Recent·Most cited

Self-amplifying mRNA expression is governed by mitochondrial machinery and ACSL4

Lara F. Tshering, Chong Wang, Qing Xiang, Sharmistha Kundu, Alicia Solórzano, Javier F. Chaparro‐Riggers, Laura Lin, Azadeh Paksa

The paper identifies mitochondrial function and ACSL4 as key regulators of self-amplifying mRNA (saRNA) expression, showing that modulating ACSL4 improves saRNA expression across cell types.

bioRxiv · Jun 13, 2025 · PreprintMolecular Biology

Fbxl10/Kdm2b is required for Kmt2b/Mll2 binding across thegenome and regulates H3K4 methylation on bivalent promoters

Fei Ji, Sharmistha Kundu, Anthony N. Anselmo, Alexander Morris, Anthony Ducasse, Ayla Ergün, Robert E. Kingston, Ruslan I. Sadreyev

bioRxiv · May 15, 2025 · PreprintMolecular Biology

Multiomic analysis of clonal development reveals new regulators of leukemic cell growth

Gracia M. Bonilla, Alexander Morris, Sharmistha Kundu, Anthony Ducasse, Grace Kirkpatrick, Nathan Elias Jeffries, Kashish Chetal, Emma Yvanovich, Jelena Milosevic, Ting Zhao, Jun Xia, Rana Barghout, David T. Scadden, Michael K. Mansour, Robert E. Kingston, , Ruslan I. Sadreyev

The paper uses multiomic analysis of leukemic clones in a mouse model to identify growth regulators and validate their roles in AML.

bioRxiv · Feb 29, 2024Molecular Biology

Changing the Waddington landscape to control mesendoderm competence

James R. Valcourt, Roya E. Huang, Sharmistha Kundu, Divya Venkatasubramanian, Robert E. Kingston, Sharad Ramanathan

This study shows that mesendoderm competence in differentiating human pluripotent stem cells can be modulated by genetic perturbations and tracked using a low-dimensional reaction coordinate.

bioRxiv · Mar 14, 2020 · PreprintDevelopmental Biology