Author

Brenda Melano

University of California, San FranciscoORCID 0000-0001-6875-8078Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alejandro Sweet-CorderoiD· 1 shared Bahar Zirak· 1 shared Brian J WooiD· 1 shared Hani GoodarziiD· 1 shared Man Hung ChoiiD· 1 shared Mehran KarimzadehiD· 1 shared Truc DinhiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Alejandro Sweet-CorderoORCID

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1 paper

Recent·Most cited

Targeting Osteosarcoma heterogeneity to improve therapeutic response

Brenda Melano, Truc Dinh, Bahar Zirak, Brian J Woo, Man Hung Choi, Mehran Karimzadeh, Hani Goodarzi, Alejandro Sweet-Cordero

The paper identifies transcription factors that drive osteosarcoma cell states and shows that modulating them can increase sensitivity to targeted therapy.

bioRxiv · Jan 2, 2025 · PreprintGenomics