Man Hung Choi

This study shows that acetic acid enhances the bactericidal effect of cobalt-doped carbon quantum dots against drug-resistant bacteria by inducing osmotic imbalances and membrane damage.

The paper identifies transcription factors that drive osteosarcoma cell states and shows that modulating them can increase sensitivity to targeted therapy.

The paper systematically identifies post-transcriptional regulatory modules by integrating multimodal data on RBP interactions and functions.

The paper introduces Mach-1, an RNA foundation model that predicts transcriptome architecture from DNA sequence, validated through experimental perturbations and CRISPR editing.