A bifidobacterial enzyme orchestrates ecology and function of infant gut bacterial community
Yangwei Shan, Nicholas Pucci, Coen Berns, Rick Hoogendijk, Myrthe Beijnvoort, Shijia Li, Alejandro Sanchez-Cano, Gertjan Kramer, Wei Du, Daniel R. Mende, Aalt D. J. van Dijk, Meike Tessa Wortel, Jianbo Zhang
This study shows how a single bacterial enzyme, D4BMY8, influences the composition and metabolism of an infant gut microbial community through its preference for the HMO lacto-N-tetraose.
bioRxiv · Apr 29, 2026 · PreprintMicrobiology