Geneva Miller

The paper develops tools for analyzing T cell behavior from live-cell imaging to improve T cell therapies by studying the effects of genetic modifications on T cell-cancer cell interactions.

Human-in-the-loop labeling of nuclear live-cell movies produced DynamicNuclearNet (over 2,621 divisions); Caliban, a tracker trained on it, beat four published trackers at division detection.

The paper investigates dynamic changes in Bdf3 chromatin occupancy during Trypanosoma brucei differentiation from bloodstream to insect stage, finding increased occupancy at genes involved in surface protein remodeling.

The paper introduces Mesmer, a deep learning algorithm for cell segmentation in tissue images, achieving human-level performance and enabling automated feature extraction.

The paper constructs a spatiotemporal atlas of the maternal-fetal interface using multiomic data to show how gestational age influences immune and stromal cell interactions and spiral artery remodeling.