Author

Stefanie Bachl

Gladstone InstitutesORCID 0009-0002-2732-2125Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:deep learning· 3 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Julia C. CarnevaleiD· 4 shared Alexander MarsoniD· 3 shared Carter ChingiD· 3 shared Archit VermaiD· 2 shared Barbara Elizabeth EngelhardtiD· 2 shared Justin EyquemiD· 2 shared Nupura KaleiD· 2 shared Adam BlaisdelliD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersCell Biology

Julia C. CarnevaleORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 5, 2026

Development of a Fully Non-Viral 1XX-enhanced BCMA CAR-T Cell Therapy for Multiple Myeloma

Alexis Talbot, K Li, Jae Hyun J. Lee…·Brian Rudolph Shy

This paper develops a non-viral BCMA CAR-T therapy using CRISPR and 1XX signaling, showing improved safety, potency, and persistence in multiple myeloma.

DOI 10.64898/2026.04.20.719660

humangenetic perturbation / CRISPR

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ImmunologybioRxivPreprintOct 5, 2025

Base-editing a single missense mutation in A20 enhances CAR-T cell efficacy

Adam Blaisdell, Stefanie Bachl, Luis R Sandoval…·Averil I. Ma

This study uses base-editing to inactivate a missense mutation in A20ZF7, enhancing CAR-T cell efficacy by reducing exhaustion and improving anti-tumor responses.

DOI 10.1101/2025.10.05.680562

humanbulk RNA-seq

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Cell BiologyPacific Symposium on Biocomputing (PSB)Peer-reviewedNov 21, 2024

Understanding TCR T cell knockout behavior using interpretable machine learning

Marcus Blennemann, Archit Verma, Stefanie Bachl…·Barbara Elizabeth Engelhardt

This study uses explainable AI to analyze live-cell imaging data and identify behavioral changes in TCR T cells with specific genetic knockouts.

1 citation

humanimaging

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Cell BiologybioRxivPreprintNov 19, 2024

Cellular behavior analysis from live-cell imaging of TCR T cell-cancer cell interactions

Archit Verma, Changhua Yu, Stefanie Bachl…·Barbara Elizabeth Engelhardt

The paper develops tools for analyzing T cell behavior from live-cell imaging to improve T cell therapies by studying the effects of genetic modifications on T cell-cancer cell interactions.

2 citations

humanimaging

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