Author

Tohru Kodama

Tokyo Metropolitan Institute of Medical ScienceORCID 0000-0001-6915-4428Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:human· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Katsushi TokunagaiD· 3 shared Makoto HondaiD· 3 shared Mihoko ShimadaiD· 3 shared Taku MiyagawaiD· 3 shared Yoshiko HondaiD· 3 shared Yuki HitomiiD· 2 shared Akihiro KarashimaiD· 1 shared Akiko HidaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersGenomics

Katsushi TokunagaORCID

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4 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJan 6, 2026

Polygenic risk scores and Mendelian randomization reveal circadian genetic contributions to idiopathic hypersomnia

Taku Miyagawa, Mihoko Shimada, Kotomi Tanida…·Makoto Honda

The paper uses polygenic risk scores and Mendelian randomization to show circadian genetic factors contribute to idiopathic hypersomnia.

DOI 10.64898/2026.01.06.26343504

humanGWAS summary statistics

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GenomicsbioRxivPreprintApr 25, 2025

Replication-associated solo-WCGW hypomethylation reflects cumulative immune activation across diseases

Mihoko Shimada, Yosuke Omae, Yuki Hitomi…·Taku Miyagawa

The paper investigates hypomethylation patterns in immune-mediated diseases, finding that solo-WCGW hypomethylation correlates with immune cell proliferation and disease-specific immune dynamics.

DOI 10.1101/2025.04.25.650620

humanDNA methylation

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GenomicsbioRxivPreprintMay 1, 2024

Multiomics analysis of narcolepsy T cells: global hypomethylation in solo-WCGW motif linked to T cell proliferation

Mihoko Shimada, Makoto Honda, Yoshiko Honda…·Taku Miyagawa

The paper identifies global hypomethylation in T cells of narcolepsy type 1 patients, linked to solo-WCGW motifs and T cell proliferation.

2 citations

humanDNA methylation

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NeuroscienceNeuroscience LettersPeer-reviewedSep 1, 2023

Contribution of default mode network to game and delayed-response task performance: power and connectivity analyses of theta oscillation in the monkey

Tohru Kodama, Takashi Kojima, Yoshiko Honda…·Masataka Watanabe

The paper examines theta oscillation in the monkey's default mode network and executive network during cognitive tasks, finding cooperative interactions and task-specific changes in theta power and connectivity.

1 citation

non-human primateelectronic health records

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