Author

Yosuke Omae

National Center for Global Health and MedicineORCID 0000-0001-9978-4869Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Katsushi TokunagaiD· 3 shared Makoto HondaiD· 2 shared Mihoko ShimadaiD· 2 shared Taku MiyagawaiD· 2 shared Akihiro FujimotoiD· 1 shared Akihiro UmezawaiD· 1 shared Akiyoshi KakitaiD· 1 shared Aritoshi IidaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersGenomics

Katsushi TokunagaORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintApr 25, 2025

Replication-associated solo-WCGW hypomethylation reflects cumulative immune activation across diseases

Mihoko Shimada, Yosuke Omae, Yuki Hitomi…·Taku Miyagawa

The paper investigates hypomethylation patterns in immune-mediated diseases, finding that solo-WCGW hypomethylation correlates with immune cell proliferation and disease-specific immune dynamics.

DOI 10.1101/2025.04.25.650620

humanDNA methylation

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GenomicsPLoS GeneticsPeer-reviewedDec 7, 2023

Exploring the genetic diversity of the Japanese Population: Insights from a Large-Scale Whole Genome Sequencing Analysis

Yosuke Kawai, Yusuke Watanabe, Yosuke Omae…·Katsushi Tokunaga

This study uses whole-genome sequencing of 9,850 Japanese samples to analyze genetic diversity, revealing population declines and natural selection linked to agriculture and food production.

38 citationstop 2%

humanwhole-genome sequencing

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GenomicsbioRxivPreprintMay 13, 2023

Identification of Region-Specific Gene Isoforms in the Human Brain Using Long-Read Transcriptome Sequencing and Their Correlation with DNA Methylation

Mihoko Shimada, Yosuke Omae, Akiyoshi Kakita…·Katsushi Tokunaga

The paper identifies region-specific gene isoforms in the human brain using long-read transcriptome sequencing and links them to DNA methylation patterns.

DOI 10.1101/2023.05.13.540603

humanlong-read sequencing

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