Gillian P. McHugo

This study identifies candidate genes for trypanotolerance in African cattle by integrating genomic and transcriptomic data from hybrid populations.

This study uses multi-omics approaches to analyze how M. bovis infection reprograms the epigenome of bovine alveolar macrophages, identifying key genes and pathways involved in the host response.

The paper develops mRNA-based classifiers using RNA-seq and machine learning to accurately distinguish bTB-positive from bTB-negative cattle and other pathogens.

This study compares gene expression in trypanotolerant and trypanosusceptible cattle during trypanosome infection across multiple tissues and time points, identifying immune-related and coagulation genes associated with trypanotolerance.

This study integrates transcriptomic, genomic, and GWAS data to identify genes and eQTLs associated with the PB transcriptome response to M. bovis infection in cattle.

The paper uses local ancestry inference tools to analyze admixture in African and European cattle populations, identifying functional consequences of ancestry on disease resistance and physiological traits.

This study uses whole-genome sequencing and SNP arrays to analyze Criollo cattle from Colombia and Venezuela, revealing African and Asian admixture and selection signatures linked to adaptive traits.

This study integrates multi-omics data from bovine and human macrophages infected with M. bovis and M. tuberculosis to identify genes and pathways associated with resistance to mycobacterial infection.

The paper identifies a 170-gene transcriptional signature in bovine peripheral blood post-M. bovis infection following PPD-b stimulation, suggesting potential biomarkers for bTB diagnostics.

The paper integrates multi-omics data with genome-wide association results to identify infection response pathways and genomic variants associated with resistance to bovine tuberculosis.

This study uses population genomics to analyze the Galway sheep breed, finding gene flow from British Leicester and Suffolk sheep, intermediate genetic diversity, and genomic signatures of selection related to meat and wool production.

This study uses genome-wide SNP data to assess genetic diversity and conservation status of Kerry cattle, revealing reduced effective population size and increased inbreeding.